Editorial Staff

Alzheimer Breakthrough Disillusionment: Confusion on FDA’s Approval of Expensive and Possibly Ineffective Drug

/in , , , /by Editorial Staff
Share on Facebook
Share on Twitter
Share on
LinkedIn
+

Hubwonk host Joe Selvaggi talks with precision medicine expert Hannah Mamuszka and Pioneer Institute’s Bill Smith about the promises and pitfalls of the newly approved Alzheimer’s drug Aduhelm, and the challenges presented when new, expensive drugs of dubious benefit are introduced to the nation’s formulary.

Guest:

Hannah Mamuszka is Founder & CEO of ALVA10, a healthcare technology firm. Hannah has spent her 20+ year career in diagnostics – both in pharma and at diagnostics companies, in the lab and on the business side. She believes that the challenges of diagnostic technology fully impacting patient care are more commercial than technical, and conceived of ALVA10 to create a mechanism to pull technology into healthcare by aligning incentives through data. She regularly speaks on issues regarding advancement of technology in healthcare, is on the Board of Directors for two diagnostic companies and writes a column on the value of diagnostics for the Journal of Precision Medicine.

Guest Host:

Dr. William S. Smith is Pioneer’s Visiting Fellow in the Life Sciences. Dr. Smith has 25 years of experience in government and in corporate roles. His career includes senior staff positions for the Republican House leadership on Capitol Hill, the White House Office of National Drug Control Policy, and the Massachusetts Governor’s office where he served under Governors Weld and Cellucci. He spent ten years at Pfizer Inc as Vice President of Public Affairs and Policy where he was responsible for Pfizer’s corporate strategies for the U.S. policy environment. He later served as a consultant to major pharmaceutical, biotechnology and medical device companies. Dr. Smith earned his PhD in political science with distinction at The Catholic University of America.

Get new episodes of Hubwonk in your inbox!

Recent episodes:

College Debt Explained: Education Pays When Students Choose Wisely

Hubwonk host Joe Selvaggi talks with American Enterprise Institute resident fellow and education economist Beth Akers about the American student debt crisis (totalling $1.6 trillion). They explore who borrows, who is in debt, and which policy choices might best serve the financial needs of every student. 

Chasing Election Integrity: Strict Voter ID Laws’ Impact on Turnout and Fraud

Joe Selvaggi talks with Harvard Business School Professor Vincent Pons about his recently released NBER paper on the effects of strict voter ID laws on voter behavior and fraud across the United States over 10 years, examining the results of the 1.6 billion observation dataset by age, race, gender, and party affiliation.

The Oldest Hatred: Calling Out Antisemitism In Its Many Forms

Hubwonk host Joe Selvaggi talks with Boston Globe opinion writer Jeff Jacoby about the troubling increase in antisemitic incidents, including the recent attack on a Boston rabbi, and how our current political rancor fans the flames of bigotry nationwide.

Court Preserves Privacy: First Amendment Ruling Defends Non-Profits From Modern-Day McCarthyism

Hubwonk Host Joe Selvaggi talks with CATO research fellow and constitutional scholar Trevor Burrus about the recent Supreme Court ruling, Americans For Prosperity Foundation v. Bonta, reaffirming the right to privacy by denying the state of California the right to compel non-profits to disclose their list of donors.

Renters’ Unsung Heroes: Small Landlords Endure Without Income or Relief

Hubwonk host Joe Selvaggi talks with MassLandlords’ Doug Quattrochi about ways landlords faced the challenges of being caught between tenants unable to pay rent during COVID-19 shutdown and having little or no programmatic relief from state and federal agencies.

Alzheimer Breakthrough Disillusionment: Confusion on FDA’s Approval of Expensive and Possibly Ineffective Drug

Hubwonk host Joe Selvaggi talks with precision medicine expert Hannah Mamuszka and Pioneer Institute's Bill Smith about the promises and pitfalls of the newly approved Alzheimer’s drug Aduhelm, and the challenges presented when new, expensive drugs of dubious benefit are introduced to the nation’s formulary.

Unintended Tax Consequences: Modeling the Effects of the Millionaire’s Tax on Massachusetts’ Economic Future

0 Comments
/
Hubwonk host Joe Selvaggi talks with Beacon Hill Institute President Dr. David Tuerck about his recent analysis of the proposed 4% surtax on incomes over $1 million in Massachusetts, and his estimate of the number of individuals who will leave the state as a result. Tuerck, an economist, used STAMP modeling tools comparing the static projections offered by proponents of the so-called "Fair Share Amendment" with a model simulation that accounts for the unintended effects of the tax.

Valuing Life-Saving Drugs: What is the Price of Life and Who Decides?

Hubwonk host Joe Selvaggi talks with Pioneer Institute visiting fellow Dr. Bill Smith about Quality Adjusted Life Years (QALY) standards, and the ways in which so-called objective cost-containing strategies use expert opinion to determine the value of a life and thereby disadvantage the elderly, disabled, and those with less common vulnerabilities to disease.

Shepherding Infrastructure Spending: Project Labor Agreements’ Effects on Community Public Construction Projects

This week on Hubwonk, host Joe Selvaggi talks with Suffolk University Economics Prof. Jonathan Haughton about his research into the effects and costs attending the adoption of Project Labor Agreements in large construction projects. The discussion focuses on Prof. Haughton’s two research pieces, The Effects of Project Labor Agreements in Massachusetts, and Do Project Labor Agreements Raise Construction Costs?, and the implications of PLAs on future projects in Massachusetts.

Origin of COVID-19: As Animal Source Evidence Eludes Scientists, Lab Leak Hypothesis Gains Purchase

This week on Hubwonk, host Joe Selvaggi talks with author and former New York Times science journalist Nicholas Wade about his recent article in the Bulletin of the Atomic Scientists on the possible origins of the SARS2 virus that caused the COVID-19 pandemic. In their conversation, they consider the possibility that, absent finding evidence of a natural jump from animals, the SAR2 virus may have come from a lab.