Editorial Staff

Alzheimer Breakthrough Disillusionment: Confusion on FDA’s Approval of Expensive and Possibly Ineffective Drug

/in , , , /by Editorial Staff
Share on Facebook
Share on Twitter
Share on
LinkedIn
+

Hubwonk host Joe Selvaggi talks with precision medicine expert Hannah Mamuszka and Pioneer Institute’s Bill Smith about the promises and pitfalls of the newly approved Alzheimer’s drug Aduhelm, and the challenges presented when new, expensive drugs of dubious benefit are introduced to the nation’s formulary.

Guest:

Hannah Mamuszka is Founder & CEO of ALVA10, a healthcare technology firm. Hannah has spent her 20+ year career in diagnostics – both in pharma and at diagnostics companies, in the lab and on the business side. She believes that the challenges of diagnostic technology fully impacting patient care are more commercial than technical, and conceived of ALVA10 to create a mechanism to pull technology into healthcare by aligning incentives through data. She regularly speaks on issues regarding advancement of technology in healthcare, is on the Board of Directors for two diagnostic companies and writes a column on the value of diagnostics for the Journal of Precision Medicine.

Guest Host:

Dr. William S. Smith is Pioneer’s Visiting Fellow in the Life Sciences. Dr. Smith has 25 years of experience in government and in corporate roles. His career includes senior staff positions for the Republican House leadership on Capitol Hill, the White House Office of National Drug Control Policy, and the Massachusetts Governor’s office where he served under Governors Weld and Cellucci. He spent ten years at Pfizer Inc as Vice President of Public Affairs and Policy where he was responsible for Pfizer’s corporate strategies for the U.S. policy environment. He later served as a consultant to major pharmaceutical, biotechnology and medical device companies. Dr. Smith earned his PhD in political science with distinction at The Catholic University of America.

Get new episodes of Hubwonk in your inbox!

Recent episodes:

Collegiate Kangaroo Courts: Title IX Rewrite Expels Free Expression and Due Process

This week on Hubwonk, host Joe Selvaggi talks with Pacific Legal Foundation Senior Fellow Alison Somin about the Biden Administration’s proposed modifications to Title IX fair treatment guidelines, challenging principles of free speech and due process, and potentially chilling the culture of free debate in American universities.

Train Wreck Averted: Labor Ties American Economy to the Tracks

This week on Hubwonk, host Joe Selvaggi talks with Dominic Pino, Thomas L. Rhodes Fellow at the National Review Institute, about his research and writing on the recently averted rail strike, including how the rail industry is organized, what labor’s demands were, and how the prospect of a nationwide rail strike exposed vulnerabilities within the American economy.

Gargantuan Graduation Gift: Biden Writes Check From Taxpayers To College Grads

This week on Hubwonk, host Joe Selvaggi talks with Dr. Beth Akers, AEI Senior Fellow, about the recent presidential executive order to cancel an estimated $500 billion in outstanding student debt. They explore who benefits, who pays, and the likely effects on tuition and the borrowing habits of future students.

MBTA’s Runaway Crisis: Legacy of Neglect Demands Comprehensive Reform

This week on Hubwonk, host Joe Selvaggi talks with Andrew Bagley, Vice President for Policy and Research at Massachusetts Taxpayers Foundation, about their recent report entitled, The MBTA Crisis is Complicated - Fixing It Will Be Too, diving into the details on why the T is in crisis and what the public must demand of policy makers to get it back on track.

The Taxman Cometh: Who Will Pay When the Newly Funded IRS Knocks?

This week on Hubwonk, host Joe Selvaggi talks with Heritage Foundation senior research fellow Rachel Greszler about the $80 billion investment in the Internal Revenue Service, focusing on the promise to limit enhanced enforcement to high earners and whether the IRS will likely need to expand its net.

Civil Society’s Stockade: Protecting Pluralism From Progressive Puritanism

This week on Hubwonk, host Joe Selvaggi talks with Noah Rothman, associate editor of Commentary magazine, about his recently released book, "The Rise of the New Puritans: Fighting Back Against Progressives' War On Fun," examining how the attempt to remoralize American culture mirrors similar social movements in the past and what concerned onlookers can do to better manage this frenzied phenomenon.

Drug Price Control: Bad Medicine for Healthcare and Region

Hubwonk host Joe Selvaggi talks with Dr. Bill Smith, Director of Pioneer Institute’s Life Sciences Initiative, about the impact of the Inflation Reduction Act on long-term health costs. They discuss the bill's unintended consequences, potential effect on the region’s vibrant pharmaceutical research and development sector, and what citizens can do about it.

Other People’s Money: Fair Share’s Populist Promises and Problems

This week on Hubwonk, host Joe Selvaggi talks with Boston Globe columnist Jeff Jacoby about November’s Massachusetts Ballot Question 1, the so-called Fair Share Amendment. They examine both the merits and timing of a graduated state income tax, as well as the effects on society of creating separate categories of taxpayers, and the dangers of setting the many against the few.

Law Enforcement Dividend: Who Benefits When Crime Is Prevented?

This week on Hubwonk, host Joe Selvaggi talks with Rafael Mangual, Manhattan Institute senior fellow, about his newly released book, Criminal (In)Justice, examining where crime is occurring in the U.S., what types of crimes those in the prison systems have committed, and the tradeoffs faced by society when considering defunding the police and reducing prison populations. 

Final Election Verdict: Conservative Compendium Comprehensively Closes 2020 Challenge Cases

This week on Hubwonk, host Joe Selvaggi talks with Ilya Somin, author and George Mason Law professor, about the newly released report on all court challenges to the 2020 presidential election entitled, Lost, Not Stolen, exploring what its authors intended to achieve, what its readers can learn from its findings, and whether such intra-party scrutiny can serve to reassure voters that their concerns about election integrity have had their day in court.